Coronaviruses and immunosuppressed patients. The facts during the third epidemic.
Identifieur interne : 000936 ( an2020/Analysis ); précédent : 000935; suivant : 000937Coronaviruses and immunosuppressed patients. The facts during the third epidemic.
Auteurs : Lorenzo D'Antiga [Italie]Source :
- Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society [ 1527-6473 ] ; 2020.
Abstract
Following the outbreak in China, the Lombardy region of Italy has become one of the areas of highest incidence of severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2). As the outbreak grew to a pandemic, many centres worldwide raised the concern that immunocompromised patients may be at high risk of developing a severe respiratory disease called COVID-19. Unlike common viral agents (such as Adenovirus, Rhinovirus, Norovirus, Influenza, Respiratory Syncytial Virus), Coronaviruses have not shown to cause a more severe disease in immunosuppressed patients. For this family of viruses the host innate immune response appears the main driver of lung tissue damage during infection.
DOI: 10.1002/lt.25756
PubMed: 32196933
Affiliations:
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